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產品分類 > 屋塵螨過敏原 > Recombinant Der f 1 (RP-DF1-1)重組粉塵螨過敏原1

Recombinant Der f 1 (RP-DF1-1)重組粉塵螨過敏原1

產品貨號:RP-DF1-1
促銷: 8720.00
價格: 8720.00

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250ug
美國Indoor
Allergen:rDer f 1 (Dermatophagoides farinae allergen 1)

Unit:250μg

Source:Pichia pastoris

Mol. Wt:~36-40kD

Purification:

Purified from Pichia pastoris culture by mAb affinity chromatography. Purity >95% by SDS-PAGE.

Concentration:

See product insert. 

Formulation:

Preservative-free and carrier-free in phosphate buffered saline, pH 7.4. Filtered through 0.22μm filter.

Storage:Store at -20oC

Notes:(1) rDer f 1 produced in P. pastoris is glycosylated and has a higher MW than the natural allergen. The doublet is due to dimer formation.

Genbank:3D6S X-ray crystal structure

PDB:
Product Resources:Recombinant Der f 1 Certificate of Analysis

Allergens are provided for research and commercial use in vitro:  not for human in vivo or therapeutic use.

References:


  1. Best EA, Stedman KE, Bozic CM, Hunter SW, Vailes LD, Chapman MD, McCall CA, McDermott MJ. A recombinant group 1 house dust mite allergen. rDer f 1, with biological activities similar to those of the native allergen. Prot Exp Pur 2000; 20:462-471.

  2. Chapman MD, Smith AM, Vailes LD, Arruda LK, Dhanaraj V, Pomés A. Recombinant allergens for diagnosis and therapy of allergic disease. J Allergy Clin Immunol 2000; 106:409-418.

  3. Chruszcz M, Chapman MD, Vailes LD, Stura EA, Saint-Remy JM, Minor W, Pomés A. Crystal structures of mite allergens Der f 1 and Der p 1 reveal differences in surface-exposed residues that may influence antibody binding. J Mol Biol, 2009;386:520-530.


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